Temporary Scientist Position - Therapeutic proteins

Regeneron is seeking a motivated and dependable temporary Scientist to support antibody bioconjugation and cell-based assay work for approximately six months. The role involves preparing antibody conjugates and fluorescent probes, maintaining mammalian cell cultures, performing binding and functional assays, supporting quality control testing, and coordinating laboratory activities for preclinical imaging studies.

Responsibilities

• Bioconjugation: Conjugating antibodies with bifunctional chelating agents (DFO, DOTA) and fluorescent probes following established protocols
• Purification and characterization: Purifying conjugates using size-exclusion chromatography; characterizing products using SE-HPLC, SDS-PAGE, and UV/Vis spectroscopy
• Cell culture: Maintaining mammalian cell lines and preparing cells for binding and functional assays
• Cell-based assays: Running binding assays, internalization assays, and functional validation experiments to confirm conjugate quality
• Quality control support: Performing basic QC testing (SE-HPLC, iTLC, gamma counting) to verify product quality
• Lab coordination: Coordinating timelines with imaging scientists and project teams; maintaining accurate electronic laboratory notebooks

Benefits

• Radiation safety training will be provided

Company

• Develops and commercializes biopharmaceutical medicines for serious diseases
• Tarrytown, New York, USA
• http://www.regeneron.com/
• Founded in 1988
• 10001+ employees

Qualifications

• Hands-on experience with protein chemistry, bioconjugation, or biochemistry lab techniques
• Comfortable with chromatographic methods (HPLC, FPLC, or column chromatography)
• Experience maintaining mammalian cell culture and running cell-based assays
• Excel at attention to detail and following established protocols
• Thrive in a collaborative, time-sensitive environment where reliability matters
• Take pride in maintaining accurate, organized laboratory records
• Eager to learn new techniques and work independently after training
• Proficiency with data analysis software (Excel, Prism, or similar) and electronic laboratory notebook systems
• Strong communication skills and ability to work effectively in a team setting
• B.S. in Chemistry, Biochemistry, Biology, Chemical Engineering, or related field with 1-3 years of laboratory experience
• Hands-on experience with protein chemistry or bioconjugation techniques, or strong foundational lab skills with willingness to learn
• Experience with chromatographic techniques and mammalian cell culture
• Comfort working in a laboratory environment where radioactive materials are handled (radiation safety training will be provided)

Required skills

• , Protein Chemistry, Bioconjugation, Chromatographic Techniques, Mammalian Cell Culture, Cell-Based Assays, GraphPad Prism

Experience

• 1-3 years